Illumina Announces Long Reads

Illumina recently announced the upcoming availability of long-read technology at the 40th Annual J.P. Morgan Healthcare Conference, in a press release and on Illumina's Genomics Research Hub.  The new long-read sequencing assay is code-named…

On an HLA Null Allele Case Study

A recent case study report describes the discovery of a novel HLA null allele and its effect on protein synthesis and gene expression (Rozar, 2021).  We occasionally deliver HLA reports that include null alleles.  This case study highlights…
hla imgt database

How Did We Discover a Novel HLA Allele?

Intro One of the pleasures of owning a genomics company is assisting client researchers with new discoveries.  Recently, one of our clients completed an 11-loci, 4-field HLA typing project for a clinical trial project.  Using Illumina Next…
SARS-COV2 spike protein

HLA Susceptibility in SARS-CoV-2

Intro Nguyen et al. recently published a paper "Human leukocyte antigen susceptibility map for SARS-CoV-2" in the Journal of Virology  Using in-silico methods, they assessed the binding affinities of MHC Class I alleles (HLA-A, HLA-B,…
Multiplexed samples reduces cost

Cost Savings with Multiplex Samples

Multiplex Sequencing Multiplexing is a method of combining two or more samples in a single sequencing run.  Multiplexing can increase the throughput of sequencing runs and save money at the same time. Conceptually, multiplexing is a fairly…
hla typing

The Cost of HLA Typing

At The Sequencing Center, one of the main services that we provide to pharmaceutical, academic, and clinical researchers is HLA Typing. HLA Typing (human leukocyte antigen) is most commonly leveraged for matching patients and donors for bone…
Genome Expression Sequencing

The Influence of Genetics on Clinical Research

Like any new technology adoption curve, genome sequencing has gone through the typical hype cycle. We start to leverage a new technology and it becomes massively hyped as the thing that will "change everything" only to realize that we don't…
press release image

Global HLA Typing Market Study Includes The Sequencing Center as a Top Vendor

As the global HLA Typing market continues to increase in demand, the number of new commercial vendors focusing on HLA Typing has stayed fairly flat relative to growth. In a new market research study conducted by Data Bridge Market Research,…
clinical diagnostics

Increasing Access to Genome Sequencing for Clinical Diagnostics

As genome sequencing continues to decrease in price and increase in demand, the desire for many clinical organizations to leverage genome sequencing as a clinical diagnostic means continues to get traction. In a recent change, the California…
genome vs exome

Genome, Exome… What’s the Difference?

Genome sequencing is all over the news lately, especially with commercial companies offering sequencing to explore a customer's ethnic background, recommended diets and fitness plans, and reveal what kinds of diseases they might potentially…
HLA typing

Find Your Perfect Match: Using HLA Typing For Successful Organ Transplants

Within clinical environments, making decisions based on precise and comprehensive data is paramount in practicing high-quality medicine. One of the more complex clinical procedures involves organ transplants. Organ transplant surgery, a high-risk…
why you need genome sequencing in clinical research

Why You Need Genome Sequencing in Clinical Research

Clinical research is a tedious process that requires precise data to validate research claims. In its current state, there are many parts of the process that break down for various reasons. Between time constraints, financial resource allocation,…
genome sequencing for clinical trials

Why You Need Genome Sequencing in Clinical Trials

The Challenges of Clinical Trials Working on clinical trials in the pharmaceutical or clinical research field can frequently be a messy process with numerous complications. You can feel blocked and delayed by staggering testing costs and lengthy…