Submit your samples – we do the rest
Submit any sample type while we handle the DNA extraction.
Our experts ensure quality throughout every stage of the sequencing process.
HLA Typing Report
Get 4-field resolution typing reports and the raw data for your analysis needs
Maximize your research budget with our cost-friendly pricing.
Get the full range of HLA services from one laboratory.
We deliver the raw data files and comprehensive HLA typing reports.
HLA Typing Gene Coverage
Our gene panel covers 11 HLA loci at 4-field resolution.
Coverage includes all relevant exons, introns, 5′-UTR’s and 3′-UTR’s.
Whole gene coverage for Class I HLA genes
Extensive coverage for Class II HLA genes
HLA-DPA1 / DPB1
HLA-DQA1 / DQB1
HLA-DRB1/ 3/ 4/ 5
HLA-E (coming soon)
HLA-G (available upon request)
HLA Typing reports include
4-field resolution for each allele
HLA typing ambiguities
P-group and G-group typing results
All projects include FASTQ data files
Major Histocompatibility Complex (MHC)
The Major Histocompatibility Complex (MHC) is a set of highly polymorphic genes in the innate and adaptive immune systems. Human Leucocyte Antigen (HLA) proteins are encoded by MHC genes.
The HLA complex is divisible into Class I and Class II alleles based on the structure and function of the encoded proteins. The extreme diversity of Class I and II alleles is responsible for their wide-ranging importance in disease states and immunity.
HLA Typing determines the compatibility of donors and recipients for organ and tissue transplantation. Mismatched donor and recipient organs or tissues can lead to their rejection by the immune system.
HLA Typing also determines one’s susceptibility to autoimmune diseases and reactions to vaccines and immunization.
MHC Related Disease States and Immunity
Type 1 diabetes
Systemic lupus erythematosus
Many additional diseases
Leading research institutions choose us
The Sequencing Center is one of the leading HLA service providers in the USA. Offering affordable, high-coverage HLA typing results and 4-field resolution, we pride ourselves on providing clients with exceptional services, including DNA extraction, library prep, sequencing and bioinformatics. We work with leading research institutes world-wide across a variety of fields including immunology, oncology, transplantation, inherited diseases, neurodegenerative diseases and drug discovery and development.