A Guide to HLA Typing with Nanopore Long Read Sequencing
The human leukocyte antigen (HLA) complex plays a critical role in the immune system’s ability to distinguish between self and non-self. Accurate HLA typing is essential for many applications, including organ and stem cell transplantation, disease association studies, drug hypersensitivity research, and more. Next-generation sequencing (NGS) has revolutionized HLA typing by enabling high-resolution, high-throughput analysis. […]