Using AlphaFold for Modeling HLA-Peptide Complexes in the Context of HLA Typing
The human leukocyte antigen (HLA) system plays a crucial role in the adaptive immune response, with HLA proteins presenting peptides derived from endogenous and exogenous proteins to T cells. Accurate modeling of the structural interactions between HLA proteins and their bound peptides is essential for understanding the molecular basis of immune recognition and has implications […]