Tag Archive for: hla genes

3D render of a DNA strandThe Sequencing Center

Unveiling the Intricacies of HLA Genetic Protein Interactions

The human immune system is delicately complex, constantly modulating responses in real-time in the face of an unending, unseen assault by a myriad of pathogens. Central to this pivotal defense mechanism is the Human Leukocyte Antigen (HLA) system,…
How do CD8*T cells kill infected cells?

HLA-A*01:01:01:01 Allele and its Impact on the Development of Malignancies

The Human Leukocyte Antigen (HLA) system plays a crucial role in immune recognition and response against pathogens and malignant cells. The HLA-A*01:01:01:01 allele has been linked to an increased risk of developing certain malignancies, such…
HLA-A*32:01 is strongly associated with vancomycin-induced drug reaction with eosinophilia and systemic symptoms

The HLA-A*32:01 Variant: A Focused Exploration for Immunology Experts

The Human Leukocyte Antigen (HLA) system is a cornerstone of the adaptive immune response, consisting of cell surface molecules encoded by the major histocompatibility complex (MHC) genes. The HLA-A gene, a member of the MHC class I family,…
Autoimmune diseases

Decoding HLA-A: Common Allele Variants and Their Clinical Implications

The Human Leukocyte Antigen (HLA) system, a group of genes within the Major Histocompatibility Complex (MHC), plays a critical role in the immune response. HLA class I molecules, including HLA-A, -B, and -C, are responsible for presenting intracellular…
HLA-B

The HLA-B Gene

The human leukocyte antigen (HLA) system is a group of genes located on chromosome 6 that play a crucial role in the immune system. The HLA-B gene is one of the many genes that make up the HLA system, and it is responsible for encoding a protein…
HLA-A

The HLA-A Gene

The human leukocyte antigen (HLA) system is a critical component of the immune system and an essential subject of medical research. The major histocompatibility complex (MHC) is an integral part of the HLA system, and the HLA-A gene is a key…
HLA Genes

HLA Typing and HLA Genes in Research: A Primer

Immunology is the study of the immune system, which includes both innate and adaptive immunity. This includes antibodies, specialized proteins that recognize foreign invaders such as bacteria or viruses; T cells, specialized white blood cells…