HLA Typing Services
11-loci & 4-field resolution
Free DNA Extraction
Skip the hassle in your lab.
We extract high quality DNA for you.
Fast Turnaround Time
Get results in days, not months
*based on project size
Get standardized HLA reports
for your organization
We can sequence any subset or combination of loci
The MHC/HLA region is a gene cluster located on human Chromosome 6. It encodes for proteins involved in the immune system’s recognition of self and non-self. And it encodes the presentation of antigens to T-cells. These proteins play an essential role in the body’s ability to recognize and respond to a wide range of pathogens and foreign cells.
The MHC/HLA is divided into two regions:
Class I MHC/HLA region encodes for proteins expressed on the surface of most nucleated cells.
Class II MHC/HLA region encodes for proteins expressed on the surface of antigen-presenting cells.
The MHC/HLA genes are highly polymorphic, the most polymorphic region in the human genome, with a vast number of different alleles that vary significantly between individuals and populations.
Matching the MHC/HLA types of donors and recipients is critical to prevent graft rejection and other complications during transplantation and transfusion procedures.
HLA typing is a critical component of both clinical and research settings. It enables the accurate identification of HLA alleles and the prediction of immune responses. Understanding the MHC/HLA systems’ complexity and diversity is essential for healthcare professionals, researchers, and patients to comprehend the mechanisms underlying immune recognition and response.
The remarkable HLA region on human Chromosome 6 is associated with a wide array of diseases:
Systemic lupus erythematosus
Type 1 diabetes
And many more
“Many thanks for the quick results. The files are so easy to look at and have very thorough data readout.”
– Michele, A2 Biotherapeutics