HLA Typing Services
Advancing precision medicine with 11-loci & 4-field resolution
HLA typing is crucial for the success of donor/recipient transplantation and the prediction of immune responses.
Provides critical insights into genetic predispositions to diseases, enabling tailored treatment plans and personalized healthcare strategies.
Facilitates the understanding of the genetic basis of diseases, aiding in the development of targeted therapies and preventive measures.
The Sequencing Center’s gene panel targets 11 HLA loci with precise 4-field resolution. This thorough coverage ensures that all relevant genetic regions are analyzed, including all pertinent exons, introns, as well as the 5′-untranslated regions (5′-UTRs) and 3′-untranslated regions (3′-UTRs), providing a complete and detailed understanding of the HLA genes.
The Sequencing Center uses Nanopore’s long-read sequencing method to deliver high-quality, 4-field resolution HLA Typing reports. Long-read sequencing uses single-molecule sequencing, generating long reads up to several kilobases. This process is followed by preparing long-read DNA libraries, sequencing on a Nanopore MinION, and then aligning the reads to the IMGT/HLA database. We deliver the Nanopore HLA Typing results in standardized reports.
Here is a collection of some common questions about HLA and our reports. You can check out our knowledge base for more helpful articles.
What are the HLA sample submission requirements?
Top immunologists rely on our precise HLA typing for their critical research projects.