Cure Diseases with HLA Typing
High-quality HLA Typing for 11 loci and 4-field resolution
HLA Typing Gene Coverage
Our gene panel covers 11 HLA loci at 4-field resolution.
Coverage includes all relevant exons, introns, 5′-UTR’s and 3′-UTR’s
Whole gene coverage for Class I HLA genes
HLA-A
HLA-B
HLA-C
Extensive coverage for Class II HLA genes
HLA-DPA1 / DPB1
HLA-DQA1 / DQB1
HLA-DRB1/ 3/ 4/ 5
HLA-E (coming soon)
HLA-G (optional)
Don’t need all 11 loci?
We can sequence any subset or combination of loci you require.
HLA Reports
HLA Typing reports include
4-field resolution for each allele
CWD status
HLA typing ambiguities
P-group and G-group typing results
Metadata
All projects include FASTQ data files
HLA sequencing has never been easier
Free DNA Extraction
Skip the hassle in your lab. We extract high quality DNA for your run.
Fast Turnaround Time
Get results in days, not months
*based on project size
Actionable Reports
Get the results you need for breakthrough research
Major Histocompatibility Complex (MHC)
The Major Histocompatibility Complex (MHC) is a set of highly polymorphic genes in the innate and adaptive immune systems. Human Leucocyte Antigen (HLA) proteins are encoded by MHC genes.
The HLA complex is divisible into Class I and Class II alleles based on the structure and function of the encoded proteins. The extreme diversity of Class I and II alleles is responsible for their wide-ranging importance in disease states and immunity.
HLA Typing determines the compatibility of donors and recipients for organ and tissue transplantation. Mismatched donor and recipient organs or tissues can lead to their rejection by the immune system.
HLA Typing also determines one’s susceptibility to autoimmune diseases and reactions to vaccines and immunization.
MHC Related Disease States and Immunity
Innate immunity
Adaptive immunity
Antigen presentation
Inflammation regulation
Autoimmune diseases
Type 1 diabetes
Multiple sclerosis
Rheumatoid arthritis
Graves’ disease
Ankylosing spondylitis
Systemic lupus erythematosus
Hashimoto’s thyroiditis
Myasthenia Gravis
Addison’s disease
Celiac disease
Many additional diseases
Top research institutions trust us
“Many thanks for the quick results. The files are so easy to look at and have very thorough data readout.”
– Michele, A2 Biotherapeutics