Tag Archive for: disease research

Scientist in a research labThe Sequencing Center

Unraveling the Complexities of HLA Mutations and Its Implications in Disease Susceptibility

As research into human leukocyte antigens (HLAs), hugely important molecular markers of the immune response, continues to grow, it consistently unveils a multifaceted array of genetic expressions that contribute to disease susceptibility. HLAs,…
Disease susceptibility

The Influence of HLA Typing on Disease Susceptibility

The Human Leukocyte Antigen (HLA) system functions as a pivotal player in the architecture of our immune response, playing a key role in the recognition and eradication of foreign pathogens. By studying the variations in HLA types, or HLA typing,…
HLA DRB1 diseases

HLA Typing: Disease States Associated with HLA-DRB1/3/4/5 Genes

This blog post presents an overview of the disease states associated with variations in the human leukocyte antigen (HLA) DRB1, DRB3, DRB4, and DRB5 genes. We will discuss the importance of HLA typing in the context of these diseases, the various…
HLA-B27 disease associations

HLA Typing: Exploring Disease States Associated with Variants of the HLA-B Gene

Human Leukocyte Antigen (HLA) typing is an essential tool in understanding genetic susceptibility to diseases, as it identifies specific alleles associated with various disease states. Among the HLA genes, the HLA-B gene has been extensively…
HLA chromosome 6

Unraveling the Complexity of HLA Genes: Disease States and Their Genetic Underpinnings

The Human Leukocyte Antigen (HLA) complex, a crucial component of the immune system, is known for its staggering genetic diversity. Located on the short arm of Chromosome 6, the HLA complex encodes for cell-surface proteins responsible for the…