Tag Archive for: long-read sequencing

3D render of a DNA strandThe Sequencing Center

A Guide to HLA Typing with Nanopore Long Read Sequencing

The human leukocyte antigen (HLA) complex plays a critical role in the immune system's ability to distinguish between self and non-self. Accurate HLA typing is essential for many applications, including organ and stem cell transplantation, disease…
3D render of a long-read dna strandThe Sequencing Center

Illumina vs Nanopore Sequencing: A Technical Comparison for HLA Typing

Human leukocyte antigen (HLA) typing is essential for bone marrow and organ transplantation. Accurate HLA typing at high resolution is critical to ensure donor-recipient matching and prevent graft rejection. Two major sequencing technologies…
Nanopre long-read sequencing

Harnessing Long-Read Sequencing in HLA Typing

The Human Leukocyte Antigen (HLA) system holds a significant role in the world of genomics, driving research in areas as diverse as organ transplantation, disease association studies, and immune response. HLA Typing, a method used…
GenDX NGS-Turbo with Oxford Nanopore Technologies

Nanopore Long-Reads Coming to HLA

GenDx announced NGS-Turbo, a long-read HLA sequencing product for Nanopore instruments. Although we will have to see the actual protocol in practice, HLA sequencing with Nanopore long-reads should offer significant benefits in relation to short-read…
Illumina long-reads

Illumina Announces Long Reads

Illumina recently announced the upcoming availability of long-read technology at the 40th Annual J.P. Morgan Healthcare Conference, in a press release and on Illumina's Genomics Research Hub.  The new long-read sequencing assay is code-named…