Human blood consists of leukocytes, thrombocytes, and erythrocytes. Only leukocytes contain a cell nucleus. Thrombocytes and erythrocytes do not contain a cell nucleus. Thus, leukocytes are the most important element when estimating the amount of DNA in human blood.
The blood of a healthy individual usually contains 425 – 750 leucocyte cells per milliliter of blood. This means that the DNA content can vary between 30 – 40 µg/mL of blood depending on the donor.
Please note that the number of leukocytes per milliliter of blood can vary considerably from 225 during immunosuppression, to 4,250 during inflammation and up to 55,000 during leukemia.
The standard mass formula for dsDNA is:
mass of dsDNA (g) = moles of dsDNA (mol) x ( (length of dsDNA (bp) x 617.96 g/mol/bp) + 36.04 g/mol)
The Sequencing Center is one of the leading HLA service providers in the USA. Offering affordable, high-coverage HLA typing results with 4-field resolution, we pride ourselves on providing clients with exceptional services, including DNA extraction, library prep, sequencing and bioinformatics. We work with leading research organizations world-wide across a variety of fields including immunology, oncology, transplantation, inherited diseases, neurodegenerative diseases, and drug discovery and development.
1020 Luke Street
Fort Collins, CO 80524
(970) 682-1288 (Direct to lab)
Click on the different category headings to find out more. You can also change some of your preferences. Note that blocking some types of cookies may impact your experience on our websites and the services we are able to offer.
These cookies are strictly necessary to provide you with services available through our website and to use some of its features.
We provide you with a list of stored cookies on your computer in our domain so you can check what we stored. Due to security reasons we are not able to show or modify cookies from other domains. You can check these in your browser security settings.
These cookies collect information that is used either in aggregate form to help us understand how our website is being used or how effective our marketing campaigns are, or to help us customize our website and application for you in order to enhance your experience.
If you do not want that we track your visit to our site you can disable tracking in your browser here:
We also use different external services like Google Webfonts, Google Maps, and external Video providers. Since these providers may collect personal data like your IP address we allow you to block them here. Please be aware that this might heavily reduce the functionality and appearance of our site. Changes will take effect once you reload the page.
Google Webfont Settings:
Google Map Settings:
Google reCaptcha Settings:
Vimeo and Youtube video embeds:
The following cookies are also needed - You can choose if you want to allow them: