FOR IMMEDIATE RELEASE Fort Collins, Colorado, 10/12/2020 – The Sequencing Center, a genome sequencing service provider for biological and clinical research, announced today that it will offer long-read sequencing services to supplement its current short-read services. With this new service, the Center will provide a comprehensive suite of whole genome and targeted sequencing solutions. “We’re […]
About Richard Casey
Richard has spent 30+ years in Next Generation Sequencing, Bioinformatics, High Performance Computing, and Software Project Management. He has previously ran Next Generation Sequencing Core lab where he combined bleeding edge computing speed with genome sequencing - a service replicated at The Sequencing Center. Richard holds a PhD in Biological Sciences and MS in Computer Science.
Intro One of the pleasures of owning a genomics company is assisting client researchers with new discoveries. Recently, one of our clients completed an 11-loci, 4-field HLA typing project for a clinical trial project. Using Illumina Next Generation Sequencing (NGS) instruments they multiplexed 48 samples for quick turnaround on a short-deadline schedule. While most samples […]
Intro Nguyen et al. recently published a paper “Human leukocyte antigen susceptibility map for SARS-CoV-2” in the Journal of Virology Using in-silico methods, they assessed the binding affinities of MHC Class I alleles (HLA-A, HLA-B, HLA-C) with all known SARS-CoV-2 8-12mer peptides from the full SARS-CoV-2 proteome. Presumably, the binding affinities of MHC Class I molecules to SARS-CoV-2 […]
Multiplex Sequencing Multiplexing is a method of combining two or more samples in a single sequencing run. Multiplexing can increase the throughput of sequencing runs and save money at the same time. Conceptually, multiplexing is a fairly straightforward process. Fig. 1 Fig. 1 shows how (two) samples are multiplexed and demultiplexed in a sequencing […]
The Paper Bean et al. recently published a report “Diagnostic gene sequencing panels: from design to report – a technical standard of the American College of Medical Genetics and Genomics (ACMG)” that provides technical standards for the design of gene panels. The report and standards will be of interest to clinical researchers and others who […]
We routinely perform bacteriophage whole genome sequencing. However, we do not currently offer phage DNA extraction services. Instead, researchers perform phage DNA extraction at their own facilities and then ship purified gDNA to our sequencing Lab. Apparently, DNA extraction for some phage species can be challenging. Therefore, we present the following option. Jakociune and Moodley, […]
The Sequencing Center is a USA-owned and operated next-generation genome sequencing company offering affordable genome sequencing and bioinformatics for research, pharmaceutical, and clinical organizations. Our services are designed for organizations performing research on bacterial, viral, and human-oriented research. Among these services, our facility offers targeted sequencing methods for research fields including inherited diseases, oncology, neurodegenerative diseases, antibiotic-resistant gene analysis, and biomarker discovery for drug development optimization.